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You are here: Home / Health / The Risks of Using Ace as a Sedative For Fearful Dogs
Ace as a Sedative for Fearful Dogs
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The Risks of Using Ace as a Sedative For Fearful Dogs

Last updated on April 18, 2019 By Puppy Leaks 12 Comments

I am not against using sedatives for fearful dogs; especially with firework season coming up. While most dogs make progress with desensitization & counter conditioning, the addition of medication can help dogs with extreme anxiety.

The purpose of this article is to highlight some of the troubling findings associated with one specific drug in particular – Acepromazine – and how it can make your dogs anxiety worse.

Many Veterinarians Prescribe Sedatives for Anxious Dogs

Anyone that’s had a panic attack or dealt with severe anxiety knows how terrifying it is; and just like us our dogs can exhibit that same level of fear in certain situations. For dogs in particular anxiety is quite common during thunderstorms or fireworks.

Many of us will be dealing with fireworks in a few weeks; and some of us are going to be asking our veterinarian for advice on medications to ease our dogs anxiety. The tranquilizer Acepromazine (Ace) is prescribed to many dogs on the 4th of July as a sedative despite it’s increasingly bad reputation.

Fear of fireworks and thunderstorms can ruin a pet’s summer, but sometimes our best efforts to help our pets feel better have the opposite effect. One of the worst offenders is the drug acepromazine, known as Ace. – Dr. Marty Becker, Don’t Ace the Fear: Why Acepromazine May Make Your Dog’s Fireworks Fears Worse

There’s been evidence that suggests Ace not only causes the fear to worsen, but that it can also cause a wide range of serious side effects. For Brachycephalic (short nosed) breeds the potential risk is especially high. In Boxers it’s been shown to cause a problem called first degree heart block, a potentially serious arrhythmia of the heart.

As well as causing sedation, the drug has an impact on the controls for blood pressure, breathing, and body temperature, with potentially serious consequences for dogs with underlying health problems. – Barbra Denempont, Acepromazine: The Sedative That is Not Safe For Your Boxer

The Problem With Using Ace as a Sedative for Fearful Dogs

Acepromazine (also known as Ace, PromAce or Aceproject) has been around for decades. It’s used to prepare dogs for surgery, surpress nausea, and calm anxious dogs. Ace was the most popular tranquilizer prescribed to help anxious dogs for a long time, though it’s popularity has been declining recently.

Ace works by blocking the receptors in the central nervous system; and the effects generally last between 6 – 8 hours. During that time many dogs have problems with their coordination; just walking around can be troublesome.

Your dog will appear sedated but his mind will be fully alert and functioning. Using Ace on a dog with extreme anxiety can make the phobia worse. Your dog will remain anxious and fearful, yet not have the ability to do anything about it because of the sedative effect.

The use of Ace has been found to make dog anxiety worse in the long term by adding even more stressful associations to the original phobia.

It’s also believed that acepromazine, used freely for noise phobia, may actually heighten pets’ sensitivity to noise. For this reason, one of my local behaviorists is especially opposed to its use during storm or fireworks season. – Dr. Patty Khuly, Why I’m Not a Big Fan When It Comes to Sedation via ‘Ace’

Sedatives themselves are no longer considered a good treatment option for dogs with anxiety due to their unreliability. To get the desired effect high doses are often used which can lead to many health risks.

High doses of sedatives can cause systemic effects such as hyvolemia (increased blood-fluid volume), hyperexcitability and extrapyrimidal side effects such as akinesia (an inability to move) or akathisia (an inability to remain still). Because of all the associated problems with sedative drug use, they are no longer recommended for use in treatment of phobias or anxiety (Neilson JC, 2002; Casey R, 2002). VetSci, Dealing With Canine Anxiety & Phobias

Here’s Dr. Karen Overall explaining the problem with using Ace for fearful dogs.

There are Numerous Medications Available for Fearful Dogs

Ace is far from the only medication available for anxiety. Today Benzodiazepines ( Benzos ) are the most commonly prescribed medications for sudden fear or panic. There are many that you probably already recognize – Xanax, Valium, Ativan, and Klonopin. But there’s also other classes of anxiety medications such as Tricyclic antidepressants, Monoamine oxidase inhibitors, SSRIs, and Buspirone.

Don’t be afraid to ask you veterinarian about all the different classes of anxiety medications that are available; every dogs anxiety is a little bit different and they should be able to help you come up with a plan that’s right for your dog.

Remember to ask about the potential side effects, how long the medication lasts, how long it takes to work, and whether or not the drug will decrease the anxiety itself. You have many options available; if your veterinarian suggests Ace don’t be afraid to voice your concerns and ask about alternatives.

It is unfortunate that acepromazine continues to be used and prescribed for fearful and anxious dogs. If your dog is being treated with this medication for his fears and phobias, please talk with your veterinarian about a more effective alternative. – Lorie Huston DVM, Is Acepromazine a Good Medication For Anxiety?

Using management techniques such as desensitization and counter conditioning in conjunction with anxiety medication for dogs with noise phobias has been found quite effective. Finding the calming techniques that work for your dog can make a big difference.

Tips For Managing Noise Phobias Without Medication

Here are some helpful articles with some great pointers on helping your dog cope with his fears during storms or fireworks.

  • How to Keep Your Dog Happy When Fireworks Go Off – Using Science!
  • It’s OK to Comfort Your Dog
  • What Kinds of Dogs Are Troubled by Fireworks, & What to do About It
  • 10 Safety & Calming Tips For Dogs During Fireworks
  • Coping With Fear of Fireworks

If you know anyone that uses sedatives for their fearful dog please pass this information along. The risk of using Ace is not worth it; rather than alleviating fear it’s known for making it worse.

I am not a veterinarian; this article is intended to provide you with information and questions to bring up with your veterinarian if you’re considering anxiety medication for your dog.

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Comments

  1. Playful Kitty says

    June 22, 2015 at 8:42 pm

    Very, very interesting! I didn’t know about ACE (I’m not sure if it is used for cats). I’m glad I read this because I will be aware of it if it ever comes up in a discussion. Personally, I use pharmaceuticals as a last resort. I try using holistic methods of resolving the problem first.

    Reply
    • Jen Gabbard says

      June 23, 2015 at 12:39 am

      From what I read Ace is used on a lot of animals; and it’s usually given as prep for surgery. But there are still some vets out there that prescribe it for dogs with anxiety although there seems to be a lot of much safer options available.

      Reply
  2. It's Dog Or Nothing says

    June 22, 2015 at 11:35 pm

    Very interesting. I always recommend sedatives as a very, very last resort. The slow metabolism of pyrs makes proper dosage difficult and can lead to more behavior problems. I wasn’t familiar with ACE – great info!

    Reply
    • Jen Gabbard says

      June 23, 2015 at 12:38 am

      Luckily I haven’t had to use any; but when I started reading about Ace & realized it’s going to get prescribed on the 4th of July I wanted to help get the word out that there’s so many better alternatives.

      Reply
  3. Chelsea Price says

    June 23, 2015 at 12:30 am

    I researched ACE a bit last year and learned the thing about the dog being sedated but fully alert in his mind. I will never use it now that I know that. Sharing your post – people need to be aware of this.

    Reply
    • Jen Gabbard says

      June 23, 2015 at 12:37 am

      I couldn’t imagine a scarier scenario – being completely stuck in a situation where you’re terrified – unable to move. Gives me the creeps just thinking about what that must be like.

      Reply
  4. Jennifer Costello says

    June 23, 2015 at 3:57 am

    Such a great article and important around this time of the year! I’ve always tried to avoid it with the Newfs as a sedative or pre-op because by dosage standards they need so much but in reality a little will do. Most vets know this but we’ve come across a few who are not familiar with the breed so we just avoid it all together!

    Reply
  5. Jodi says

    June 23, 2015 at 4:01 pm

    Wow, I did not know this. Neither of my dogs seem to be bothered by fireworks but when they are, I close up the house, put on the AC and turn up the TV. In the past few months Sampson has become very unsettled when it is windy, those times he usually does okay if we can go somewhere and sit together. I’ve shared it on Facebook as I know some of my friends have anxious/fearful dogs. I can’t imagine how helpless a dog would feel taking this medication.

    Reply
  6. Anne( www.whiskerstopaws.com ) says

    June 26, 2015 at 5:25 pm

    I agree that there are better choices than Acepromazine for fireworks anxiety . We have good luck with Thundershirtrs at the vet hospital I work at.

    Reply
  7. Camille Schake says

    June 26, 2015 at 7:52 pm

    What a great article! Years ago at the vet clinic where I worked, we used acepromazine mostly as a pre-surgical tranquilizer, since one of its benefits was decreasing any nausea that might be experienced from the anesthetic gas. However, one of our doctors also prescribed it for sedation and anxiety, while the other doctor preferred Valium instead. Personally I never liked using these drugs at all for anxiety, since as a Vet Tech I knew there were always risks. To me, behavior modification and desensitization always made more sense, if those were options for the patient.

    Reply
  8. Crystal says

    May 25, 2018 at 5:42 pm

    Thank for writing this article. Very informative. I recently had my dog fixed and I later found out that he was prescribed ‘Ace’ for freaking out after coming out of surgery. It was not written down on his invoice at all, we were told that he was given a sedative but didn’t know what one. Later that day he completed attacked my sister and I and I started researching the sedatives out there. I came across your article and a bunch of others. After reading them I phoned the vet back and asked what they gave them and he said ‘Ace’. I asked him why that sedative and he said because he was thrashing about and making noises. I was very upset that I wasn’t told or asked if this was okay to give him. With all the other anxiety medication out there why this? The next day he became more himself and a bit more alert with us. We have a ferret too so of course our concerns were extremely high. I just wish we were told of this so called ‘Ace’ and actually talked with the veterinarian who preformed the procedure in person. Very disturbed by all this. This medication should never be allowed to be administered after coming out of surgery or anxiety. We wish we never put him through this.

    Reply
    • Jen Gabbard says

      May 25, 2018 at 6:18 pm

      Thank you for sharing your story. I’m not sure why some veterinarians still prescribe Ace either; as you said there’s so many other anxiety medications to choose from. One of the possible side effects of Ace is agressiveness and stimulation, so the fact that your veterinarian didn’t even tell you about it makes it even worse. Any medication like that should be discussed beforehand and properly disclosed.

      Reply

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